Aromatic compositions for the inhibition of exoprotein...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – N-c doai

Reexamination Certificate

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C435S252100, C424S401000, C424S405000

Reexamination Certificate

active

07026354

ABSTRACT:
Compositions including an aromatic compound for inhibiting the production of exoproteins by Gram positive bacteria are disclosed. The aromatic inhibitory compounds of the present invention have the general formula:wherein R1is selected from the group consisting of H,—OR5, —R6C(O)H, —R6OH, —R6COOH, —OR6OH, —OR6COOH, —C(O)NH2,and NH2and salts thereof; R5is a monovalent saturated or unsaturated aliphatic hydrocarbyl moiety; R6is a divalent saturated or unsaturated aliphatic hydrocarbyl moiety; R7is a trivalent saturated or unsaturated aliphatic hydrocarbyl moiety; R8is a monovalent substituted or unsubstituted saturated or unsaturated aliphatic hydrocarbyl moiety which may or may not be interrupted with hetero atoms; R2, R3, and R4are independently selected from the group consisting of H, OH, COOH, and —C(O)R9; R9is hydrogen or a monovalent saturated or unsaturated aliphatic hydrocarbyl moiety.

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PCT/US02/28756 PCT International Search Report completed Dec. 18, 2002.

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