Aromatic amine derivatives, their production and use

Details Aromatic amine derivatives, their production and use Aromatic amine derivatives, their production and use

2007-01-09

2007-01-09

Mckenzie, Thomas (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S616000, C568S077000, C568S306000, C544S400000

Reexamination Certificate

active

09807081

ABSTRACT:
Compounds of a formula:wherein Ring A represents an optionally-substituted aromatic ring; Ring B represents an optionally-substituted cyclic hydrocarbon group; Z represents an optionally-substituted cyclic group; R1represents a hydrogen atom, an optionally-substituted hydrocarbon group, an optionally-substituted heterocyclic group, or an acyl group; R2represents an optionally-substituted amino group; D represents a chemical bond or a divalent group; E represents —CO—, —CON(Ra)—, COO—, N(Ra)CON(Rb)—, —N(Ra)COO—, —N(Ra)SO2—, N(Ra)—, —O—, —S—, —SO— or —SO2— (in which Raand Rbeach independently represent a hydrogen atom or an optionally-substituted hydrocarbon group); G represents a chemical bond or a divalent group; L represents (1) a chemical bond or (2) a divalent hydrocarbon group optionally having from 1 to 5 substituents selected from;(i) a C1-6alkyl group,(ii) a halogeno-C1-6alkyl group,(iii) a phenyl group,(iv) a benzyl group,(v) an optionally-substituted amino group,(vi) an optionally-substituted hydroxy group, and(vii) a carbamoyl or thiocarbamoyl group optionally substituted by:<1> a C1-6alkyl group,<2> an optionally-substituted phenyl group, or<3> an optionally-substituted heterocyclic group, and optionally interrupted by —O— or —S—; X represents an oxygen atom, an optionally-oxidized sulfur atom, an optionally-substituted nitrogen atom, or an optionally-substituted divalent hydrocarbon group; Y represents two hydrogen atoms, an oxygen atom or a sulfur atom; . . . means that R2may be bonded to the atom on Ring B to form a ring, or their salts, and a method for producing them.

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