Aromatic amine compounds their method of preparation and pharmac

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514316, 514317, 514318, 514321, 514324, 514326, 514330, 514331, 544360, 544364, 544365, 544366, 544367, 544374, 544376, 544379, 544386, 544391, 544394, 544398, 544399, 546186, 546189, 546190, 546193, 546194, 546198, 546205, 546209, 546210, 546212, 546213, H01N 4360, C07D21106, C07D40500

Patent

active

053170202

ABSTRACT:
Aromatic amine derivatives of the general formula (I) ##STR1## or salts of the derivatives with mineral or organic acids are useful as neurokinin receptor antagonists.

REFERENCES:
patent: 3941795 (1976-03-01), Carr et al.
patent: 4059621 (1977-11-01), Vincent et al.
patent: 4485108 (1984-11-01), Jozic
patent: 4559349 (1985-12-01), Storni
patent: 4916156 (1990-04-01), Mosse et al.
patent: 4942169 (1990-07-01), Sugimoto et al.
Decarie et al., "Characterization of the peripheral action of neuropeptide K on the rat cardiovascular system", European Journal of Pharmacology, 213 (1992) 125-131.
Takano et al., "Role of NK-1 receptor in central cardiovascular regulation in rats: studies on a novel non-peptide antagonist, CP-96,345, of substance P NK-1 receptor", Neuroscience Letters, 139 (1992) 122-125.
Frossard et al., "Minireview-Tachkinin Receptors and the Airways", Life Sciences, vol. 49 (1991), 1941-1953.
Fleetwood-Walker et al., "The involvement of neurokinin receptor subtypes in somatosensory processing in the superficial dorsal horn of the cat", Brain Research, 519 (1990) 169-182.
Lam et al., "Inhibition of carrageenan induced inflammation in the rat knee joint by substance P antagonist", Annals of the Rheumatic Diseases 1989: 48: 928-932.
Lotz et al., "Substance P Activitation of Rheumatoid Synoviocytes: Neural Pathway in Pathogenesis of Arthritis", Science, Reports, vol. 235, (Feb. 20 1987) 893-894.
McGillis et al., "Substance P and immunoregulation", Federation Proc. 46: 196-199; (1987).
Dion et al., "Receptors for neurokinins in human bronchus and urinary bladder are of the NK-2 type", European Journal of Pharmacology, 178 (1990) 215-219.
Giuliani et al., "NK.sub.2 tachykinin receptors and contraction of circular muscle of the human colon: characterization of the NK.sub.2 receptor type", European Journal of Pharmacology, 203 (1991) 365-370.
Advenier et al., "Relative potencies of neurokinins in guinea pig trachea and human bronchus", European Journal of Pharmacology, 139 (1987) 133-137.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Aromatic amine compounds their method of preparation and pharmac does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aromatic amine compounds their method of preparation and pharmac, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aromatic amine compounds their method of preparation and pharmac will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1628317

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.