Aromatase inhibitors

Details Aromatase inhibitors Aromatase inhibitors

1990-02-08

1993-07-13

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514177, 514169, 552638, 552641, 552642, 552505, 540114, 549555, C07J 100, C07J 1300, A61K 31565

Patent

active

052273750

ABSTRACT:
Novel aromatase inhibitors are disclosed for use in therapeutic preparations for treatment of estrogen-dependent diseases. The compounds are specified 7.alpha.-substituted androstanedione and androstenedione derivatives which show a strong inhibitory activity towards aromatase. The invention includes synthesis and pharmaceutical compositions of said compounds.

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