Aromatase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514363, 514365, 514372, 514383, 548262, 548250, 548146, 548214, 548336, A61K 31425, A61K 3141

Patent

active

047359609

ABSTRACT:
This invention provides a method of inhibiting aromatase and treating estrogen-dependent diseases in mammals by administering certain azole derivatives. Certain azole derivatives and their pharmaceutical formulations are also provided.

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Draber et al. (IV); CA76:59632e (1972) N-(1,1,1-trisubstituted) methylazoles.
Sumitomo I (CA:95:203952w), 1981.
Humburg et al., "1,5-Disubstituierte 1,2,4-triazolverbindungen", Liebigs Ann. Chem., 1387 (1982).
Chemical Abstracts 95:203952w (1981).
Chemical Abstracts 96:68990k (1982).

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