Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-06-18
1987-04-21
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514397, 514399, 548250, 548252, 548255, 548256, 548262, 548336, 548346, A61K 31415, C07D40504, C07D23358
Patent
active
046597301
ABSTRACT:
This invention provides certain azole derivatives and their pharmaceutical formulations. Also provided is a method of inhibiting aromatase and treating or preventing estrogen-dependent diseases in mammals by administering the azole derivatives.
REFERENCES:
patent: 3636002 (1972-01-01), Godefred
patent: 4115578 (1978-09-01), Miller et al.
patent: 4144347 (1979-03-01), Stern
patent: 4235893 (1980-11-01), Brodie et al.
patent: 4278800 (1981-07-01), Rentzea et al.
patent: 4284641 (1981-08-01), Thorogood
patent: 4342775 (1982-08-01), Cozzi et al.
patent: 4468404 (1984-08-01), Rane et al.
patent: 4503062 (1985-03-01), Gravestock
patent: 4510149 (1985-04-01), Cozzi et al.
Siiteri et al., Handbook of Physiology-Endocrinology II, Part I, pp. 615-629 (1977).
Goodman and Gilman's, "The Pharmacological Basis of Therapeutics", 6th Edit., p. 1304 (1980).
Harris, Expl. Cell. Biol., 53, pp. 1-8 (1985).
Brodie et al., Endocrinology, 100, pp. 1684-1695 (1977).
Tseng et al., Obstet and Gyn., 63 (2), pp. 150-154 (1984).
Berkowitz et al., Amer. J. Epidemiology, 121 (2), pp. 238-245 (1985).
Tseng et al., J. Clin. Endocrinology and Metabol. 55 (5), pp. 1029-1031 (1982).
Coombes et al., Lancet, pp. 1237-1239, (Dec. 1, 1984).
Santen et al., Ann. Int. Med., 96, pp. 94-101 (1982).
Barone et al., J. Endocrin. and Metabol., 49, pp. 672-676 (1979).
Cancer Research, 42, (8) (Supplement) (1982).
M. Yamato, et al., "Reactivity of Isocoumarins IV . . .", Chem. Pharm. Bull., 30 (3), 843 (1982).
Chemical Abstracts 95:203829m (1981).
Chemical Abstracts 82:72873c (1975).
Chemical Abstracts 87:4873f (1977).
Hirsch Kenneth S.
Jones Charles D.
Taylor Harold M.
Briscoe Kurt G.
Conrad Robert A.
Eli Lilly and Company
Jiles Henry R.
Whitaker Leroy
LandOfFree
Aromatase inhibiting imidazole derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aromatase inhibiting imidazole derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aromatase inhibiting imidazole derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-752221