Aromatase inhibiting 4(5)-imidazoles

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514396, 5483351, 5483361, 5483401, 5483411, A61K 31415, C07D23364

Patent

active

054399289

ABSTRACT:
Novel 4(5)-imidazole derivatives of specified formula and their non-toxic salts possess selective aromatase inhibiting properties, which are valuable in the treatment of estrogen dependent diseases e.g. breast cancer.

REFERENCES:
patent: 4544664 (1985-10-01), Karjalainen et al.
patent: 5006543 (1991-04-01), Boyle
patent: 5098923 (1992-05-01), Karjalainen et al.

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