Aripiprazole, olanzapine and haloperidol pamoate salts

Details Aripiprazole, olanzapine and haloperidol pamoate salts Aripiprazole, olanzapine and haloperidol pamoate salts

2006-01-17

2006-01-17

Chang, Celia (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S327000, C424S422000, C424S426000, C544S363000, C546S217000

Reexamination Certificate

active

06987111

ABSTRACT:
The invention relates to the discovery that pamoate salts of haloperidol and aripiprazole result in a good to superior long acting and/or extended release profile. Thus, in one aspect of the invention, the invention includes pamoate salts of haloperidol or aripiprazole. Preferably, the pamoate salt is characterized by a ratio of haloperidol to pamoate of 1:1 or 2:1. The pamoate salt can be crystalline, such as a needle or a dense crystal, such as described in the Figures.The invention further relates to methods of treating an individual in need thereof comprising administering a pharmaceutical composition comprising a pamoate salt of haloperidol and aripiprazole.

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