Arginine mimic derivatives as enzyme inhibitors

Details Arginine mimic derivatives as enzyme inhibitors Arginine mimic derivatives as enzyme inhibitors

1994-06-17

1997-06-10

Chang, Ceila

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514316, 514318, 546191, 546193, 546208, 546210, A61K 31445, C07D40112

Patent

active

056375999

ABSTRACT:
The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease slates in mammals characterized by abnormal thrombosis.

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