Arginine deiminase from a Mycoplasma arginini strain

Details Arginine deiminase from a Mycoplasma arginini strain Arginine deiminase from a Mycoplasma arginini strain

1994-02-25

1995-12-12

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435227, C12N 980, C12N 978

Patent

active

054749280

ABSTRACT:
A novel arginine deiminase of an approximately 45,000 molecular weight derived from mycoplasma having an ability to decompose arginine, and the method of manufacturing this novel enzyme from mycoplasma. This enzyme is an effective anti-cancer agent, as it shows anti-cancer activities both in vitro and in vivo.

REFERENCES:
Sasaki et al., In Vitro, vol. 20, No. 5, May 1984, pp. 369-375.
Chen et al., J. Clin. Microb., vol. 16, No. 5, Nov. 1982, pp. 909-919.
Lin, J., J. Gen. Microb., vol. 132, 1986, pp. 1467-1474.
Fujsaki et al., J. Biochem., vol. 89, No. 1, 1981, pp. 257-263.
Takahara et al., J. Biochem, vol. 94, No. 6, 1983, pp. 1945-1953.
Baur et al., Eur. J. Biochem, vol. 179, No. 1, Jan. 1989, pp. 53-60.
Journal Of Chromatography, vol. 440, 1988, pp. 131-140 Elsevier Science Publishers B. V., Sugimura, et al.

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