Arginase II

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

530350, C07K 1447, C12N 978

Patent

active

060543086

ABSTRACT:
The invention relates to Arginase II polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.

REFERENCES:
patent: 5912159 (1999-06-01), Vockley et al.
Hillier L et al., "Human EST: 5' similar to human Arginase I", EMBL Databases, Accession No. T64853, Mar. 6, 1995, XP002077230.
Jenkinson C. et al., "Isolation and characterization of a novel human arginase" FASEB J., vol. 10, No. 6, Apr. 30, 1996, pp. A1372-abstract 2146, XP002077226.
Vockley J. et al., "Cloning and Characterization of the human type II arginase gene", Genomics, vol. 38, Dec. 1, 1996, pp. 118-123, XP002077224.
Morris S et al., "Human type II arginase: sequence analysis and tissue-specific expression" Gene, vol. 193, Jul. 9, 1997, pp. 157-161 XP002077225.
Patterton D. and Shi Y: "Thyroid hormone-dependent differential regulation of multiple arginase genes during amphibian metamorphosis", Journal of Biological Chemistry, vol.. 269, No. 41, Oct. 14, 1994, pp. 25328-25334, XP002077223.
Hrabak A et al: "Comparison of substrate and inhibitor specificity of arginase and nitric oxide (NO) synthase for arginine analogues and related compounds in murine and rat macrophages" Biochemical and Biophysical Research Communications, vol. 198, No. 1, Jan. 14, 1994, pp. 206-212, XP002077227.
Spector E. et al.: "Subcellular location and differential antibody specificity of arginase in tissue culture and whole animals", Intl. J. Devl. Neuroscience, vol. 12, No. 4, Jun. 12, 1994, pp. 337-342, XP002077228.
Grody W. et al: "Arginase deficiency manifesting delayed clinical sequelae and induction of a kidney arginase isozyme" Hum. Genet., vol. 91, 1993, pp. 1-5, XP002077229.
Entrez (ver. 7.0) released Oct. T08457, ISSN 1065-707X, National Center for Biotechnology Information.
Adams et al, 1993 Nature Genetics 4:373-380.
Gotoh et al. 1996 FEBS Lett. 395: 119-122.
Jenkinson et al. 1996 Comp. Biochem. Physiol. 114B(1): 107-132.
Baker et al. 1982 in: The Study of Biology, f ourth Edition, Addison-Wesley Publ. Co., Reading MA (p. 9).
Grody et al. 1989 J. Clin. Invest. 83: 602-609.
Michels et al. 1978 Clin. Genet. 13: 61-67.
Spector et al. 1983 Ped. Res. 17(12): 941-944.
Am. J. Hum. Genet. (Suppl) 55(3): A139, Sep. 1994, Program and Meeting Abstracts--1994 Annual Meeting.
Cederbaum et al. 1979 Ped. Res. 13: 827-833.
Cederbaum et al. 1977 Ped 90(4): 569-573.
Dizikes et al. 1986 Biochem. Biophys. Res. Commun. 141(1): 53-59.
Catalogue of Cell Lines & Hybridomas, 7th edition, 1992 from the American Type Culture Colletion, p. v.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Arginase II does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Arginase II, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Arginase II will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-992502

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.