Arg a human gene related to but distinct from abl proto-oncogene

Details Arg a human gene related to but distinct from abl proto-oncogene Arg a human gene related to but distinct from abl proto-oncogene

1990-07-30

1997-12-02

Wax, Robert A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 536 232, 536 2431, C07H 2104, C12Q 168

Patent

active

056937784

ABSTRACT:
The invention concerns the isolation and sequencing of a new gene, arg, related to the abl proto-oncogene. The gene gets transcripted to two mRNA's; which in turn form two proteins. Antibodies, oligonucleotide probes and assays of detecting the arg gene, its mRNA and its protein products are also objects of the invention.

REFERENCES:
patent: 4599305 (1986-07-01), Witte et al.
Fainstein et al. (1989) Oncogene 4: 1477-1481.
Perego et al. (1991) Oncogene 6(10): 1899-1902.
Reddy et al. (1983) Proc. Natl. Acad. Sci. 80: 3623-3627.
Kruh et al. 1986. Science, 234:1545-1548.
Kruh et al. 1990. Proc. Natl. Acad. Sci. 87:5802-5806.

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