Aralkyl-alcohol peiperazine derivatives and their uses as...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S255010, C514S255050, C544S358000, C544S360000, C544S363000, C544S364000, C544S377000

Reexamination Certificate

active

07576086

ABSTRACT:
Aryl alkanol piperazine derivatives of the formulaand pharmaceutical compositions comprising the same. Also disclosed are methods for treating depression using the pharmaceutical composition. Compounds of the invention have excellent dual inhibitory actions to the uptake of the mono-amines neurotransmitter, good antidepressant activities and minor side effects.

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patent: WO 0250061 (2002-06-01), None
Lutz, R., et al., Antimarlarials. Some Piperazine Derivatives, Journal of Organic Chemistry, 12, 771-5 (1947).
Baltzly, R., et al., Preparation of N-monosubstituted and unsymmetrically disubstituted piperazines, Journal of the American Chemical Society, 66, 263-6 (1944).
Kaufmann, et al., Multiresidue Analysis of Tranquilizers and the Beta-blocker Carazolyl in Meat by Liquid Chromotography/tandem Mass Spectrometry, Rapid Communications in Mass Spectrometry 15(18), 1747-1751 (2001).

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