Aqueous ophthalmic formulations and methods for preserving same

Details Aqueous ophthalmic formulations and methods for preserving same Aqueous ophthalmic formulations and methods for preserving same

1991-05-02

1995-06-13

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Elemental chlorine or elemental chlorine releasing inorganic...

514557, 514912, A61K 3314, A61K 3119

Patent

active

054240786

ABSTRACT:
Stabilized chlorine dioxide is a preservative for ophthalmic formulations. The stabilized chlorine dioxide, when employed as a preservative ophthalmic formulations is preferably present in an amount of from about 0.0002 or about 0.002 to about 0.02 weight/volume percent. The aqueous ophthalmic formulations, in addition to the stabilized chlorine dioxide and the water which functions as a vehicle for the formulations, contains an ophthalmically acceptable tonicity component effective to maintain the osmolality of the formulation at least about 200 mOsmol/kg, and a buffer to maintain the pH of the ophthalmic formulation within an acceptable physiological range. A method for preserving aqueous ophthalmic formulations utilizing stabilized chlorine dioxide is also set forth.

REFERENCES:
patent: Re32672 (1988-05-01), Huth et al.
patent: 2436134 (1948-02-01), Aston
patent: 2477631 (1949-08-01), Levy
patent: 3123521 (1964-03-01), Wentworth
patent: 3278447 (1966-10-01), McNicholas
patent: 3591515 (1971-07-01), Lovely
patent: 3819828 (1974-06-01), McCoy
patent: 3910296 (1975-10-01), Karageozian et al.
patent: 4084747 (1978-03-01), Alliger
patent: 4104190 (1978-08-01), Hartshorn
patent: 4123376 (1978-10-01), Gray
patent: 4456510 (1984-06-01), Murakami
patent: 4459217 (1984-07-01), Bogie
patent: 4499077 (1985-02-01), Stockel et al.
patent: 4568517 (1986-02-01), Kaspar et al.
patent: 4614549 (1986-09-01), Ogunbuyi et al.
patent: 4618444 (1986-10-01), Hudson et al.
patent: 4654208 (1987-03-01), Stockel et al.
patent: 4689215 (1987-08-01), Ratcliff
patent: 4690773 (1987-09-01), Ogunbuyi et al.
patent: 4696811 (1987-09-01), Ratcliff
patent: 4786492 (1988-11-01), Ratcliff
patent: 4788053 (1988-11-01), Ratcliff
patent: 4792244 (1988-12-01), Ratcliff
patent: 4793989 (1988-12-01), Ratcliff
patent: 4837009 (1989-06-01), Ratcliff
patent: 4851213 (1989-07-01), Ratcliff
patent: 4855135 (1989-08-01), Ratcliff

Affiliated with

Also associated with

Rating

Aqueous ophthalmic formulations and methods for preserving same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aqueous ophthalmic formulations and methods for preserving same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aqueous ophthalmic formulations and methods for preserving same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1307804