Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1987-08-11
1989-11-07
Howard, Jacqueline V.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514970, A61K 3121
Patent
active
048793086
ABSTRACT:
Nitroglycerin injection that is free of the customary organic solvents and has an extended shelf life of at least 1 year, consisting essentially of water, lactose, and nitroglycerin. Sodium chloride or dextrose may be added during manufacture or upon diluting with an infusion. Commerically safe manufacture and stable dispersion are assured by mixing lactose adsorbate, containing nitroglycerin, with water at high shear so that no nitroglycerin droplets coalesce. Stability is maintained by filtering and filling operations using nonreactive, nonleaching, nonadsorptive materials.
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Alam Abu S.
Joshi Utpal G.
Kapoor John N.
Mehta Jairaj U.
Sayeed Fakrul A. A.
Howard Jacqueline V.
Lyphomed, Inc.
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