Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Reexamination Certificate
2005-06-14
2005-06-14
Low, Christopher S. F. (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
C558S199000
Reexamination Certificate
active
06906047
ABSTRACT:
This invention is directed towards a ready-to-use aqueous composition of ifosfamide. In one embodiment, the invention is directed to an aqueous ifosfamide composition which comprises ifosfamide, a pharmaceutically acceptable buffer, and water. The concentration of ifosfamide in the composition may be between about 40 mM and about 400 mM. The concentration of buffer in the composition may be between about 10 mM and about 260 mM. The molar ratio of ifosfamide to buffer may be between about 0.5:1 to about 20:1. The pH of the composition may be between about 4 and about 8.
REFERENCES:
patent: 9507083 (1995-09-01), None
patent: 9918973 (1999-04-01), None
HCAPLUS, DN 130:316628, Bayer, WO 9918973, (1999), abstract only.
Burkhart Michael
Mirejovsky Dorla
Delacroix-Muirheid C.
Gensia Sicor Pharmaceuticals, Inc.
Low Christopher S. F.
Sutherland & Asbill & Brennan LLP
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