Aqueous gel containing tricalcium di(1-hydroxy-3-aminopropane-1,

Details Aqueous gel containing tricalcium di(1-hydroxy-3-aminopropane-1, Aqueous gel containing tricalcium di(1-hydroxy-3-aminopropane-1,

1982-05-17

1984-05-01

Lovering, Richard D.

Compositions

Preservative agents

Anti-corrosion

252DIG11, 424 19, 424 54, 424204, 424DIG6, B01J 1300

Patent

active

044460520

ABSTRACT:
Calcium 1-hydroxy-3-aminopropane-1,1-diphosphonate forms a gel when mixed with water. As compared to soluble salts of APD, the gel provides slow systemic release and reduced tissue damage when used in the treatment of certain disorders in warm blooded animals.

REFERENCES:
patent: 3101301 (1963-08-01), Siegal et al.
patent: 3608067 (1971-09-01), Irani
patent: 3683080 (1972-08-01), Francis
patent: 3962432 (1976-06-01), Schmidt-Dunker
patent: 4054598 (1977-10-01), Blum et al.
patent: 4200539 (1980-04-01), Burnham et al.
patent: 4327039 (1982-04-01), Blum et al.
P. Gysen and G. Heynen, Anal. Chem. Symp. Ser., (1980), (Biochem Biol. Appl. Isotachopheresis), pp. 85-87.

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