Aqueous formulation containing a piperidinylcyclopentylheptenoic

Details Aqueous formulation containing a piperidinylcyclopentylheptenoic Aqueous formulation containing a piperidinylcyclopentylheptenoic

1992-06-08

1993-06-22

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic nonactive ingredient containing other...

Carbohydrate or lignin, or derivative

514 58, 514 59, 514317, 514530, 514531, 514778, A61K 4700, A61K 31215, A61K 31445, A61K 31715

Patent

active

052216950

ABSTRACT:
Aqueous formulations comprising [1R-[1.alpha.(Z),2.beta.,3.beta.,5.alpha.]]-(+)-7-[5-[[(1,1'-biphenyl)-4-y l]methoxy]-3-hydroxy-2-(1-piperidinyl) cyclopentyl]-4-heptenoic acid or its hydrochloride salt and an unsubstituted or substituted .alpha.-, .beta.- or .gamma.-cyclodextrin have been found which are particularly useful in the treatment or prophylaxis of conditions mediated by thromboxane A.sub.2. Suitable aqueous formulations include injections, oral preparations such as syrups and capsules and inhalation preparations.

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