Aqueous fludarabine phosphate composition

Details Aqueous fludarabine phosphate composition Aqueous fludarabine phosphate composition

2006-12-26

2006-12-26

Jiang, Shaojia Anna (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S046000, C514S048000, C514S388000, C514S449000, C424S457000, C424S458000, C424S460000, C424S463000, C424S469000, C424S470000, C536S055300, C536S027120, C536S026710

Reexamination Certificate

active

07153840

ABSTRACT:
This invention is directed towards a ready-to-use aqueous composition of fludarabine phosphate. In one embodiment, the invention is directed to an aqueous fludarabine phosphate composition which comprises fludarabine phosphate, a base, and water. The concentration of fludarabine phosphate in the composition may be between about 0.5 mg/mL and about 50 mg/mL. The pH of the composition may be between about 5.5 and about 7.1.

REFERENCES:
patent: 4988722 (1991-01-01), Yuen
patent: 5081110 (1992-01-01), Kim et al.
patent: 6046322 (2000-04-01), Tilstam et al.
patent: 6174873 (2001-01-01), Wrenn, Jr.
International Search Report for related PCT International Application No. PCT/US03/16395, filed May 23, 2003 (Oct. 30, 2003).

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