Aqueous dispersion of hydrogel nanoparticles with inverse...

Details Aqueous dispersion of hydrogel nanoparticles with inverse... Aqueous dispersion of hydrogel nanoparticles with inverse...

2004-12-09

2011-11-01

Ariani, Kade (Department: 1651)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

C424S487000, C977S702000, C977S897000, C977S906000

Reexamination Certificate

active

08048450

ABSTRACT:
An aqueous dispersion of hydrogel nanoparticles and methods of making the aqueous dispersion of hydrogel nanoparticles having an interpenetrating polymer network (“IPN”) are described. The uniformed sized mono-disperse IPN nanoparticles have inverse thermo gelation properties that allow therapeutic medications to be uniformly distributed in a liquid form of the aqueous dispersion of hydrogel nanoparticles. Such medications can then be released from a solid form of the aqueous dispersion of hydrogel nanoparticles in time dependant manor.

REFERENCES:
patent: 5135627 (1992-08-01), Soane
patent: 5403893 (1995-04-01), Tanaka et al.
patent: 6632457 (2003-10-01), Sawhney
patent: 6639014 (2003-10-01), Pathak et al.
patent: 6749868 (2004-06-01), Desai et al.
Kubota et al. , Journal of Applied Polymer Science, 1998, vol. 70, p. 1027-1034.
Kubota et al. , Journal of Applied Polymer Science, 2001, vol. 80, p. 798-805.
Gan & Lyon , J. Am. Chem. Soc., 2001, vol. 123, No. 31, p. 7511-7517.
Plucktaveesak et L. , XIIIth International Congress on Rheology, Cambridge, UK, 2000, 3-307-309.
Hennink & Nostrum , Advanced Drug Delivery, 2002, vol. 13, p. 13-36.
Kubota et al., Journal of Applied Polymer Science, 2001, vol. 80, p. 789-805.
Dhara et al. Macromol Chem. Phys. 2001, vol. 202, p. 3617-3623.
Gan & Lyon, J. Am. Chem. Soc., 2001, vol. 123, No. 31, p. 7511-7517.
Hennink & Nostrum, Advanced Drug Delivery, 2002, vol. 13, p. 13-36.
Bouillot et al., Colloid Polym Sci, 2000, vol. 278, p. 74-79.
Qiu et al. , Advanced Drug Delivery, 2001, vol. 53, p. 321-339.
Cai et al., Journal of Applied Polymer Science, 2002, vol. 83, p. 169-178.
Jeong et al., Advanced Drug Delivery Reviews, 2002, vol. 54, p. 37-51.
Kurisawa et al., Journal of Controlled Release, 1998, vol. 54, p. 191-200.
Jones et al., Macromolecules, 2000, vol. 33, p. 8301-8306.
Hennink & Nostrum, Advanced Drug Delivery Reviews, 2002, vol. 54, p. 13-36.
Gan et al., J Am. Chem. Soc., 2001, vol. 123, p. 7511-7517.
Benee, L. S., Snowden, M. J., Chowdhry, B. Z., Langmuir, 2002, 18, 6025.
Bouillot, P., Vincent, B. Colloid and Polymer Science 2000, 278, 74-79.
Bromberg, L.E., Ron, E.S., Temperature-responsive gels and thermogelling polymer matrices for protein and peptide delivery, Adv. Drug Deliv. Rev. 31 (1998) 197.
Chen, L., Gong, J., Osada, Y. Macromolecular Rapid Communications 2002, 23(3), 171-174.
Durand, D., Hourdet, Synthesis and thermoassociative properties in aqueous solution of graft copolymers containing poly(N-isopropylacrylamide) side chains, Polymer 40 (1999) 4941.
Gao, J., Frisken, B. J., Langmuir, 2003, 19, 5217-5222.
Gao, J., Hu, Z., Langmuir, 2002, 18 (4), 1360-1367.
Gutowska, Y.H., Bae, H., Jacobs, J., Feijen, Sung Wan Kim, Macromolecules, 1994, 27, 4167.
Han, C.K., Bae, Y. H., Polymer 1998, 39, 2809-2814.
Hayakawa, M. Onda, T. Tanaka, T., and K. Tsujii, K., Langmuir 1997, 13, 3595.
Hirotsu, S., Hirokawa, Y., Tanaka, T. J. Chem. Phys. 1987, 87, 1392.
Hu, X., Xia, H., Hydrogel nanoparticle dispersions with inverse thermoreversible gelation, Adv. Mat. 16 (2004) 305.
Ilmain, T. Tanaka, E. Kokufuta, Volume transition in a gel driven by hydrogen bonding, Nature (London, United Kingdom) 349 (1991) 400.
Jeong, B., Kim, S. W., Bae, Y. H.,Adv. Drug Del. Rev. 2002, 54, 37-51.
Jones, C. D., Lyon, L.A., Macromolecules 2000, 33, 8301-8306.
Katono, H., Maruyama, A., Sanui, K., Ogata, N., Okano, T., Sakurai, Y. J Control Rel 1991, 16, 215-227 273:464-472.
Lee, K., and Asher, S. A., J. Am. Chem. Soc., 122, 9534-9537 (2000).
Pelton, R., Adv. Colloid Interface Sci. 2000, 85, 1-33.
Routh, A. F., Vincent, B., Langmuir, 2002, 18, 5366-5369.
Sassi, A. P. Shaw, A. J. Han, S. M., Blanch, H. W. and Prausnitz, J. M., Partitioning of proteins and small biomolecules in temperature- and pH-sensitive hydrogels, Polymer 37 (1996) 2151.
Tsujii, K., Hayakawa, M., Onda, T., Tanaka, T., Macromolecules 1997, 30, 7397.
Wang, C. J., Hu, Z. B., Chen, Y. Y., Li, Y. Macromolecules 1999, 32, 1822-1827.
Weissman, J.M., Sunkara, H. B., Tse, A. S., Asher, S. A., Science 1996, 274, 959-960.
Wu, J.Z., Zhou, B., Hu, Z. B., Phys. Rev. Lett. 2003, 90, 048304.
Wu, J.Z., Zhou, C.S. Macromolecules 1996, 29, 1574.
Wu, J.Z., Huang, G., Hu, Z. B., Macromolecules 2003, 36, 440-448.
Xia, X.H., Z. B. Hu, Synthesis and light scattering study of nanoparticles with interpenetrating polymer networks, Langmuir 20 (2004) 2094.
Yoshida, R., Uchida, K., Kaneko, Y., Sakai, K., Kikuchi, A., Sakurai, Y., and Okano, T., Comb-type grafted hydrogels with rapid de-swelling response to temperature changes, Nature 374 (1995) 240.
Holtz, S. A. Asher, Nature 1997, 389, 829-832. c) L. Liu, P. Li, and S. A. Asher, Nature, 397, 141-144 (1998).

Affiliated with

Also associated with

Rating

Aqueous dispersion of hydrogel nanoparticles with inverse... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aqueous dispersion of hydrogel nanoparticles with inverse..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aqueous dispersion of hydrogel nanoparticles with inverse... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4283790