Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1998-04-24
2000-09-26
Kishore, Gollamudi S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
424 62, A61K 9127, A61K 700
Patent
active
061239593
ABSTRACT:
The present invention discloses aqueous compositions comprising liposomes of phospholipids, and at least one competitive inhibitor of an enzyme for the synthesis of melanin, in combination with at least one non-competitive inhibitor of an enzyme for the synthesis of melanin. The invention also includes the use of the compositions of this invention for the de-pigmentation of skin.
REFERENCES:
patent: 5279834 (1994-01-01), Meybeck
Holdsworth (1972) Chromones in Aloe Species, Part I --Aloesin, PM 19(4):322.
Holdsworth (1972) Chromones in Aloe Species, Part II --Aloesone, PM 22(1):54.
Lee and Kim (1995) Cosmetics and Toiletries 110:51-56.
Yagi et al. (1987) Planta Medica 515.
Hirata and Suga (1977) 32c:731-734, Biologically Active Constituents of Leaves and Roots of Aloe arborescens var. natalensis.
Gombert (1997) Cosmetics and Toiletries Manufacture Worldwide, pp. 151-157.
Blume Gabriele
Jones Kenneth
Padmapriya Abeysinghe
Teichmuller Ernst E.
Kishore Gollamudi S.
Univera Pharmaceuticals, Inc.
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