Aqueous antimicrobial composition having improved stability

Details Aqueous antimicrobial composition having improved stability Aqueous antimicrobial composition having improved stability

1979-06-20

1980-11-04

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424267, 424320, A01N 3718, A01N 3743, A01N 3440

Patent

active

042320410

ABSTRACT:
Aqueous antimicrobial compositions which comprise a halogenated amide antimicrobial, such as 2,2-dibromonitrilopropionamide, a water miscible organic solvent such as a straight chain polyalkylene glycol (e.g., polyethylene glycol 200) or an ether thereof (e.g., a mono- or di-lower alkyl and/or phenyl ether) and water and which have improved stability are obtained by ensuring that such compositions are substantially free of glycols having a molecular weight of less than about 70 and of salts of organic acids. The resulting improved compositions exhibit reduced rates of decomposition of the halogenated amide antimicrobial relative to the corresponding aqueous compositions containing salts of organic acids and/or glycols having a molecular weight of less than about 70.

REFERENCES:
patent: 3689660 (1972-09-01), Burk et al.
patent: 3751444 (1973-08-01), Solem et al.
patent: 4022605 (1977-05-01), Konya et al.

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