Aprosamine derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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424180, C07H 1522

Patent

active

043628664

ABSTRACT:
New aprosamine derivatives having the reinforced antimicrobial activity against gram-positive and negative bacteria with less side effects than apramycin, and produced by chemical modification of 8'-hydroxy group of aprosamine obtained by means of hydrolysis of apramycin.

REFERENCES:
patent: 3691279 (1972-09-01), Thompson et al.
patent: 3853709 (1974-12-01), Stark
patent: 3876767 (1975-04-01), Ose
Abe et al., "The Jour. of Antibiotics", vol. XIV, 1981, pp. 1434-1443.
O'Connor et al., "Chem. Abst.", vol. 85, 1976, p. 21,760(t).

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