Apramycin derivatives

Details Apramycin derivatives Apramycin derivatives

1981-10-22

1983-01-25

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, A61K 3171, C07H 1522

Patent

active

043704751

ABSTRACT:
Novel 5,6-dideoxyapramycin derivatives having reinforced antimicrobial activity against gram-positive and negative bacteria with less side effects than apramycin, and produced by sulfonylation of 5- and 6-hydroxy groups and the subsequent reductive removal of sulfonates.

REFERENCES:
O'Connor et al., "Chem. Abst.", vol. 85, 1976, p. 21, 760(t).

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