Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process...
Reexamination Certificate
2005-11-08
2005-11-08
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
C435S440000, C435S471000, C435S108000, C435S243000, C435S813000, C435S252300, C435S252330, C435S252100
Reexamination Certificate
active
06962794
ABSTRACT:
This invention describes methods for enhancing carbon flow into a pathway of a host cell to enhance the biosynthetic production of compounds therefrom, the host cells being selected based on being phenotypically Pts−/glucose+. Such host cells are capable of transporting glucose without consuming PEP, resulting in conservation of PEP which can be re-directed into the pathway in order to enhance the production of desired compounds along the pathway. Pts−/glucose+mutants have been shown to be advantageous for the enhanced production of the aromatic amino acids.
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Berry Alan
Mejia Noemi
Valle Fernando
Genecor International, Inc.
Genencor International Inc.
Prouty Rebecca E.
Universidad Nacional Autonoma de Mexico
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