Application of botulinum toxin to the management of neurogenic i

Details Application of botulinum toxin to the management of neurogenic i Application of botulinum toxin to the management of neurogenic i

1997-09-04

2000-05-16

Lankford, Jr., Leon B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 514825, 514885, 4242821, 424810, 435842, A61K 3800, A61K 4500, A61K 4505

Patent

active

060637684

ABSTRACT:
The present invention provides a method for the use of at least one serotype or a combination of serotypes of Botulinum neurotoxin either alone or in combination with other peptides or fusion proteins, that when administered in a safe and effective amount, antagonize and therefore decrease or block inflammation induced by the neurogenic mechanisms underlying or associated with inflammatory disorders, in particular, arthritis.

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patent: 5677274 (1997-10-01), Leppla et al.
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Asada et al. Laser Ther. vol. 3, No. 2, pp. 77-82, 1991.
Caudle et al. Orthopedics. vol. 12, No. 5, pp. 735, 1989.
Lianga et al. J. Rheumotol. vol. 13, No. 1, pp. 230-231, 1986.

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