Appetite-stimulating agents and remedies for anorexia

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Reexamination Certificate

active

07015241

ABSTRACT:
An appetite-stimulating agent and a therapeutic agent for anorexia, each comprising, as an active ingredient, a sulfonamide derivative or sulfonic acid ester derivative represented by the following general formula (I):wherein the ring A represents a monocyclic or bicyclic aromatic ring which may be substituted,the ring B represents a 6-membered unsaturated hydrocarbon ring or a 6-membered unsaturated heterocyclic ring containing one nitrogen atom as a heteroatom, each of which may be substituted,the ring C represents a 5-membered heterocyclic ring containing one or two nitrogen atoms, which may be substituted,W represents a single bond or —CH═CH—,X represents —N(R1)— or an oxygen atom,Y represents a carbon atom or a nitrogen atom,Z represents —N(R2)— or a nitrogen atom, andR1and R2may be identical or different and each represents a hydrogen atom or a lower alkyl group, or a pharmacologically acceptable salt thereof, or a hydrate thereof.

REFERENCES:
patent: 5721246 (1998-02-01), Yoshino et al.
patent: 6469043 (2002-10-01), Haneda et al.
patent: 1 070 705 (2001-01-01), None
patent: 08-231505 (1996-09-01), None
patent: 2000-309534 (2000-11-01), None
patent: WO 98/15530 (1998-04-01), None
patent: WO 98/27081 (1998-06-01), None
See-Lasley, et al, Manual of Oncology Therapeutics, 1981, p. 9.

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