Apparatus for ultrasonic stirring of liquids in small volumes

Details Apparatus for ultrasonic stirring of liquids in small volumes Apparatus for ultrasonic stirring of liquids in small volumes

2011-07-19

2011-07-19

Sorkin, David (Department: 1774)

Agitating

By vibration

Vibrator attached to mixing chamber wall or platform

C366S116000, C366S127000

Reexamination Certificate

active

07980752

ABSTRACT:
Ultrasound-assisted contactless stirring of liquids in a resonator cell by microparticles is achieved by repeated creating and destruction of nodal patterns associated with standing waves of various resonance frequencies causing continuous movements of microparticles inside the cell. Swept-frequency sonication technique includes using constant or variable rate of frequency change as well as a stepwise change of frequency of the transducer within a predefined range. Other useful provisions include initial detection of the set of resonance frequencies and periodic refreshing of that set. Control systems are described including means to automatically detect the resonance frequencies and maintain the operation of the transducer thereon. Advantageous designs of the apparatus are described for use in microstirring, mixing of liquids using magnetic microbeads, microbubbles, microtiter plates, microarray plates, etc.

REFERENCES:
patent: 4398925 (1983-08-01), Trinh et al.
patent: 4759775 (1988-07-01), Peterson et al.

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