Chemistry: molecular biology and microbiology – Apparatus – Differentiated tissue perfusion or preservation apparatus
Patent
1987-09-08
1992-04-28
Lacey, David L.
Chemistry: molecular biology and microbiology
Apparatus
Differentiated tissue perfusion or preservation apparatus
435292, 435299, 43524023, 435240243, 427 2, 600 36, 623 15, C12M 300, A61F 210
Patent
active
051089262
ABSTRACT:
Disclosed are apparati for the precise positioning of cells into highly organized tissue structures. In particular, ink jet printers and graphics plotters are modified to allow their use in the preparation of tissue structures which are suitable for use in the treatment of burn patients. Cells are positioned by the use of computer-controlled placement of cell adhesion materials such as fibronectin to a substratum which is suitable for maintaining cell growth, followed by allowing cells to attach to those areas of the substratum where the cell adhesion material has been placed. Alternatively, specific placement of cells onto substrata is obtained by the computer-controlled placement of cells directly. These apparati may be even further modified and improved by providing a controlled biological environment in the area of the substratum, thus providing an integral unit for the production of organized tissues.
REFERENCES:
patent: 4656130 (1987-04-01), Shoshan
patent: 4664945 (1987-05-01), Maeda et al.
patent: 4791069 (1988-12-01), Hovarka et al.
patent: 4874500 (1989-10-01), Madou et al.
patent: 4877745 (1989-10-01), Hayes et al.
Klebe et al. (1987), "Fibronectin,--Mediated Attachment of Mammalian Cells to Polymeric Substrata", Chapter 38 of Proteins at Interfaces, ACS Symposium Series 343, eds. Brush and Horbett, pp. 615-628.
Klebe et al. "Adhesive Substrates for Fibronectin", Journal of Cellular Physiology, vol. 109, pp. 481-488 (1981).
Beisner William H.
Board of Regents , The University of Texas System
Lacey David L.
LandOfFree
Apparatus for the precise positioning of cells does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Apparatus for the precise positioning of cells, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus for the precise positioning of cells will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1248938