Apparatus for the chemical synthesis of molecular arrays

Details Apparatus for the chemical synthesis of molecular arrays Apparatus for the chemical synthesis of molecular arrays

1996-09-16

1999-11-09

Horlick, Kenneth R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 435 911, 4352831, 4352851, 4352862, 4352864, 4352865, 4352872, 4352873, 422129131, 42214911, 422111, 2391022, B01J 1900, C07H 2100

Patent

active

059817330

ABSTRACT:
An apparatus for the automated synthesis of molecular arrays. A jetting device is employed along with a reaction chamber to dispense reagents used in the synthesis onto the substrate. A positioning system moves the substrate from the jet to the reaction chamber. A controller controls the movement of the substrate and the application of the reagents so that the synthesis is carried out according to a pre-determined procedure. The apparatus will synthesize nucleotides in an array of micron-size spots according to a pattern selected by the operator immediately prior to synthesis.

REFERENCES:
patent: 5472672 (1995-12-01), Brennan
patent: 5474796 (1995-12-01), Brennan
patent: 5529756 (1996-06-01), Brennan
Blanchard et al., "High-density oligonucleotide arrays", Biosensors & Bioelectronics, 11: 687-690 (1996).

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