Apparatus for sterilizing bone grafts

Chemical apparatus and process disinfecting – deodorizing – preser – Physical type apparatus – Apparatus for treating solid article or material with fluid...

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422307, 435283, 435316, A61L 204, A61L 224, A01N 102, C12M 102

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054298105

ABSTRACT:
An apparatus for sterilizing bone grafts, such as human spongiosa grafts, includes a container for receiving the bone graft together with a quantity of sterile liquid sufficient to cover the bone graft. A penetrable self-sealing closure member is provided for closing the container, whereupon the container is initially heated at a given sterilizing temperature for a constant first period of time, and is subsequently heated for a variable second period of time, the duration of which is a function of the size of the bone graft. The container is then cooled to room temperature, and a transfer tube arrangement inserted at one end through the closure member to transfer the liquid within the first container to a second container. The sterilized bone graft remaining in the first container is frozen, and the liquid in the second container is analyzed for infectious diseases.

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H. Knaepler, S. Laubach & L. Gotzen, Die Knochenbank--ein standardisiertes Verfahren?, Chirurg (1990) 61: pp. 833-836.
H. Knaepler et al, Experimentelle Untersuchungen zur thermischen Desinfektion und Sterilisation allogener Knochentransplantate, Unfallchirung (1992) 95: pp. 1-8.

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