Liquid purification or separation – With alarm – indicator – register – recorder – signal or...
Patent
1998-01-08
1998-12-15
Reifsnyder, David A.
Liquid purification or separation
With alarm, indicator, register, recorder, signal or...
210 97, 210109, 2103601, 2103801, 422 72, 422 8205, 422101, 435 3, 435 13, 436164, 436177, 494 1, 494 2, 494 3, 494 10, 604 6, B01D 2176, G01N 2101
Patent
active
058491783
ABSTRACT:
An apparatus is provided for centrifuging and further automatically handling a container (110) for separating a component, such as fibrin monomer, from blood. The container (110) comprises a cylindrical member (27) and a piston displaceable in said cylindrical member, said piston comprising a tubular piston rod (8) extending through a top wall (73). The piston divides the cylindrical member (27) into a first chamber (70) positioned above said piston between said piston and the top wall (73), and a second chamber positioned below said piston. The top wall (73) of the container comprises an extension (90) defining a circumferential slit surrounding the outer side of the piston rod (8), whereby one end of said slit communicates in the axial direction with the first chamber. In addition, the first chamber communicates through a plurality of channels with the second chamber. The apparatus according to the invention comprises a supporting turntable (101) with means for releasably retaining the cylindrical member (27), said supporting turntable being connected to a first activating means (105) for rotating said supporting turntable (101) with the container (110) about the central axis thereof, as well as a rotatably journalled piston activating mechanism (113, 118) adapted to activate the piston (55) by means of a second activating means (115). The apparatus comprises an optical blood cell detector (130) which is adapted to emit a light beam obliquely towards the piston rod (8) through the extension (90) of the top wall (73) and the slit (91), and which comprises a detecting means for observing the intensity of the reflected light beam. The apparatus further comprises a control means (131) for controlling the piston activating mechanism (113, 118) in response to the measurements of the detecting means.
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Holm Niels Erik
Jorgensen Glenn A.
Bristol--Myers Squibb Company
Furman Theodore R.
Kilcoyne John K.
Krieger Stuart E.
Reifsnyder David A.
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