Apparatus for prothrombin testing

Chemistry: physical processes – Physical processes – Crystallization

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23259, G01N 3316, B01L 1100

Patent

active

039516067

ABSTRACT:
A manually operable, disposable diagnostic device which is useful for the rapid measurement of coagulation rates consists of a uniform bore reaction tube which may be used to take up the sample and contains the appropriate amounts of lyophilized reagents required to conduct individual tests such as that for prothrombin time. In an example, calibration marks on the tube have been correlated in terms of prothrombin times. The position at which a liquid sample becomes immobilized as it descends down the tube corresponds to the test time. The rate of descent is controlled by a limiting orifice or by inclining the tube to the vertical axis.

REFERENCES:
patent: 2171823 (1939-09-01), Baker
patent: 2664403 (1953-12-01), Weichselbaum
patent: 2685800 (1954-08-01), Natelson
patent: 3233975 (1966-02-01), McCormick
patent: 3434859 (1969-03-01), Benjamin
patent: 3560163 (1971-02-01), Mittleman
patent: 3692487 (1972-09-01), Sanz
patent: 3838013 (1974-09-01), Bergeron
Chem. Abstr., V. 6: 1016 (1912).
J. Lab. & Clin. Med., V. 53, pp. 617-621 (1959).

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