Liquid purification or separation – With heater or heat exchanger
Patent
1998-06-25
2000-07-04
Walker, W. L.
Liquid purification or separation
With heater or heat exchanger
2103216, 2102572, 210259, 422101, 436177, 530382, B01D 6300
Patent
active
060833831
ABSTRACT:
This invention relates generally to apparatuses and processes for preparing fibrinogen glue from autologous plasma. More particularly, this invention relates to a novel apparatus comprising a plasma membrane separator to extract and separate the autologous plasma from other undesirable compositions in the blood. The autologous plasma is transferred to a membrane separator to provide separation of the fibrinogen from other compositions with a desirable amount of ether or other suitable solvents containing an-OH group in the presence of a mixing means. The fibrinogen so separated is transferred to a fibrinogen collector which is connected to a vacuum pump through a sterile filter to remove the ether or other suitable solvents contained thereof. A freezer is provided to maintain the autologous plasma in the membrane separator and the fibrinogen in the fibrinogen collector at a desirable temperature. Additionally, a constant temperature bisyringe serves to keep the fibrinogen liquid and mixed with thrombin to form a homogeneous clotting to achieve hemostasis and tissue approximation. A second embodiment which provides a method of producing fibrin glue without the need of ether or organic solvents is also disclosed.
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Huang Xun Yang
Liang Gang
Liang Yan
Chang C. P.
Walker W. L.
Ward Richard W.
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