Apparatus for preparing a biocompatible matrix

Details Apparatus for preparing a biocompatible matrix Apparatus for preparing a biocompatible matrix

2005-06-02

2008-11-18

Ketter, James S (Department: 1636)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Solid support and method of culturing cells on said solid...

C435S402000, C424S424000

Reexamination Certificate

active

07452720

ABSTRACT:
An apparatus and method of using the apparatus to prepare a biocompatible biodegradable matrix capable of supporting cells to form an implantable or engraftable surgical device. A matrix-forming fluid is contained within a chamber defined by top and bottom surfaces of a thermally conductive material and spacers defining the thickness of the matrix. The chamber is then cooled to freeze the solution at a controlled rate, resulting in a matrix with a desired and uniform thickness having symmetric and uniform reticulations. The apparatus and method reproducibly forms such a matrix, which may be populated with cells for transplantation and engraftment into a wound.

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European Patent Office,International Search Report, PCT/US03/06479, mailed Jul. 23, 2003 (3 pgs.).

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