Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Automatic analytical monitor and control of industrial process
Patent
1985-06-10
1987-10-06
Lacey, David L.
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Automatic analytical monitor and control of industrial process
422111, 422132, 422134, G05D 700
Patent
active
046982086
ABSTRACT:
An automated apparatus for conducting a broad range of organic synthesis reactions includes a first column carring a polymeric support, a second column carrying a second polymer support, and conduits connecting the two columns and permitting the circulation of fluids therebetween. In operation each polymeric support carries a different reactive species and a liquid medium containing a specifically selected intermediate reactant, in a solvent, is circulated between the columns in order to remove the reactive species from the first support by reaction with the intermediate, and to permit the reactive species thus removed to react with the reactive second support, at the same time regenerating the original intermediate reactant. Sensors are placed at the entrance and exit of the second column carrying the second polymeric support. The sensors are capable of sensing the relative presence of the intermediate reactant. When the same content of intermediate reactant is sensed at both the entrance and exit of the second column, the computer causes the circulation to be automatically stopped as this indicates complete loading of the second column.
REFERENCES:
patent: 3475392 (1969-10-01), McCoy et al.
patent: 3649202 (1972-03-01), Bajer et al.
patent: 4017498 (1977-04-01), Hopkins
patent: 4065412 (1977-12-01), Dryer
patent: 4115305 (1978-09-01), Hornby et al.
patent: 4119589 (1978-10-01), Horn et al.
patent: 4296086 (1981-10-01), Whitehead
patent: 4305906 (1981-12-01), Mikasa et al.
patent: 4483964 (1983-11-01), Urdea et al.
Rebek, Jr. J., "Mechamistic Studies Using Solid Supports: the Three-Phase Test", Tetrahedron vol. 35, pp. 723-731, Pergamon Press, Ltd., 1979.
Akelah, A. et al., "Application of Functionalized Polymers in Organic Synthesis" Chem. Rev., 1981, 81: 557-587.
Mathur, N. K. et al., "Functionalization of Styrene-Based Polymers via Choromethylation and Other Methods", Polymers as Aids in Organic Chemistry, pp. 18-36.
Kraus, M. A. et al., "Polymeric Reagents", Macromol. Rev., vol. 15, pp. 55-105.
Cohen, B. J. et al., "Wolf and Lamb" Reactions: Equilibrium and Kinetic Effects in Multipolymer Systems" J. Am. Chem. Soc., 1981, 103, 7620-7629.
Cohen B. J. et al., "Organic Synthesis Involving Multipolymer Reactions, Polymeric Trityllithium", J. Am. Chem. Soc. 1977, 99:12, pp. 4165-4166.
Patchornik, A., "Some Novel Developments in the Use of Polymeric Reagents Multiphase and Multistep Reactions", Nouv. J. Chim. 6, 12, 639-43, 1982.
Journal of the American Chem. Soc. 97, (454-456 (1975)).
Chem. Abstr. 87, (1977) 98467b.
Chem. Abstr. 84, (1976) 165450u.
Chem. Abstr. 85, (1976) 89499v.
Pass Shimeon
Patchornik Abraham
Shai Yechiel
Lacey David L.
Yeda Research and Development Co. Ltd.
LandOfFree
Apparatus for multipolymer synthesis of organic compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Apparatus for multipolymer synthesis of organic compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus for multipolymer synthesis of organic compounds will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2116472