Optical: systems and elements – Compound lens system – Microscope
Reexamination Certificate
2006-08-15
2006-08-15
Dunn, Drew A. (Department: 2872)
Optical: systems and elements
Compound lens system
Microscope
C359S396000, C356S244000, C356S246000
Reexamination Certificate
active
07092154
ABSTRACT:
An apparatus is provided with a cell culture container having a cell culture region made of a hole formed on a substrate, a semi-permeable membrane covering a top plane of the cell culture region and a culture medium replacement part provided over the semi-permeable membrane, a mechanism for supplying a cell culture medium into the cell culture container, and a microscopic optical mechanism for enabling long-term observation of the cell within the cell culture region. This apparatus makes it possible to culture a cell group originating from a particular single cell, to perform culture and observation while identifying cells to be subjected to interaction during the process of culturing cells, and observe a difference in variation between the particular cell and other cells. There is also provided a mechanism which makes it possible to collect only a cell assuming a particular state and perform analysis or biochemical measurement of a gene of the cell, an expressed mRNA and the like.
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Inoue Ippei
Kaneko Kunihiko
Wakamoto Yuichi
Yasuda Kenji
Yomo Tetsuya
Dunn Drew A.
Japan Science and Technology Corporation
Pritchett Joshua L.
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