Apparatus for measuring the genetic sequence of biopolymers

Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing

Reexamination Certificate

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C435S006120, C435S288700, C204S600000, C204S643000

Reexamination Certificate

active

07125710

ABSTRACT:
The present invention relates to apparatus for measuring the genetic sequence of electrically charged biopolymers by means of hybridization. The measuring apparatus comprises a container that contains a biopolymer and can be removed from the apparatus, and electrodes that apply an electric field to the container and are electrically insulated from the container. When an electric field is applied to the container, suspended biopolymeric molecules are attracted toward the positive electrode, thus increasing the speed of hybridization.

REFERENCES:
patent: 5605662 (1997-02-01), Heller et al.
patent: 5632957 (1997-05-01), Heller et al.
patent: 6051380 (2000-04-01), Nerenberg et al.
patent: 6238909 (2001-05-01), Choong et al.
patent: 2001/0005718 (2001-06-01), Wen-Tung et al.
patent: 1120646 (2001-08-01), None
patent: WO 9739144 (1997-10-01), None
patent: 013848-2 (2001-05-01), None
RG Sosnowski et al “Rapid Determination of single base mismatch mutation in DNA hybrids by direct electric field control” Feb. 97, Proc. Natl Acad Sci USA vol. 94, pp. 1119-1123.

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