Optics: measuring and testing – Blood analysis
Patent
1980-10-24
1982-10-05
McGraw, Vincent P.
Optics: measuring and testing
Blood analysis
356 73, 356336, 356440, 422 81, 2504612, G01N 3348, G01N 2164
Patent
active
043525580
ABSTRACT:
In apparatus for measuring reaction and/or diffusion of particles suspended in a fluid, which apparatus includes a supply tube for supplying a stream of the particle-containing fluid, a tapered tube surrounding the supply tube for providing a first entraining fluid stream and for encasing the particle-containing fluid in the first entraining fluid stream for the purpose of hydrodynamically focusing the particle-containing stream into a thin stream enclosed by the first fluid and in which the particles are separated from one another, an outlet for passage of the thin stream and first fluid stream after leaving the tube, a device producing a radiation beam which intersects the thin particle-containing stream, a detector disposed for detecting the radiation emanating from the separated particles, and a pulse evaluation circuit connected to the detector, there is provided a further tube surrounding the supply tube and forming a further entraining fluid stream concentric with the particle-containing stream and the first entraining fluid stream, surrounding the particle-containing stream and flowing therewith through the tapered tube, the further entraining fluid stream having a composition selected to interact with the particles.
REFERENCES:
patent: 4110043 (1978-08-01), Eisert
"Quantitative Aspects of Rapid Microfluorometry for the Study of Enzyme Reactions and Transport Mechanisms in Single Livine Cells", Kohen et al., pp. 207-217 in the text Fluorescence Techniques in Cell Biology, published by Springer Verlag, 1973, Heidelbery-New York.
Gesellschaft fur Strahlen-und Umweltforschung mbh, Munchen
McGraw Vincent P.
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