Apparatus for measuring glycohemoglobin

Details Apparatus for measuring glycohemoglobin Apparatus for measuring glycohemoglobin

1993-05-11

1994-09-20

Therkorn, Ernest G.

Liquid purification or separation

With means to add treating material

Chromatography

2105021, 210635, 210656, 422 70, B01D 1508

Patent

active

053486498

ABSTRACT:
In separation column 23 is packed a filler consisting of an inorganic or organic porous substance having carboxyalkyl group and dihydroxyboronyl group. Thus, the separation column 23 can concurrently perform the procedure of separating glycohemoglobin, hemoglobin and hemoglobin derivatives in blood and the procedure of decomposing labile-type hemoglobin in blood into glucose and hemoglobin to remove the labile-type hemoglobin, when a diluted blood sample on sample table 19 along with eluents 8 to 10 is transferred to the separation column 23. Then, stable-type hemoglobin in the eluate from the separation column 23 is measured by UV-VIS detector 25.

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Nathan, Clin. Chem. 28/3, Rapid Method of Eliminating Labile Glycosylated Hemoglobin, 1982, pp. 512-515.
Nathan, Clin. Chem. 27/7, Labile Glycosylated Hemoglobin Contributes to Hemoglobin A, pp. 1261-1263, (1981).

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