Chemical apparatus and process disinfecting – deodorizing – preser – Control element responsive to a sensed operating condition
Patent
1994-03-14
1996-07-16
Warden, Jill
Chemical apparatus and process disinfecting, deodorizing, preser
Control element responsive to a sensed operating condition
209217, 209225, 209232, 210222, 422 44, 422 99, 435 2, 435 721, 435962, 435971, 436526, 436806, 436807, 604 6, G01N 33553, B01L 1100
Patent
active
055364756
ABSTRACT:
An apparatus for magnetic cell separation using paramagnetic microbeads includes a base upon which is movably carried a rocker member. The rocker member carries both a primary processing container in which a mixture of liquid with cells and paramagnetic microbeads is received; and a primary magnet movable from a first position adjacent to the primary container to magnetically capture the microbeads, and a second position spaced from the primary container to magnetically release the microbeads. The mixture of liquid with cells and microbeads is agitated by tilting motions of the rocker assembly, thereby achieving the binding of target cells to microbeads. The paramagnetic microbeads, with bound target cells, are captured and released by movements of the primary magnet between its first and second positions. A secondary magnet is placed downstream from the primary magnet to capture any paramagnetic microbeads which might escape from the primary magnet. Also provided is an interconnected container apparatus for use to contain and appropriately conduct the liquid, cells, and microbeads.
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Hardwick R. Alan
Moubayed Ahmad-Maher
Baxter International Inc.
Guthrie Janice
Ludlow Jan M.
Schiffer Michael
Warden Jill
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