Apparatus for liquid chromatography for separating AIC component

Details Apparatus for liquid chromatography for separating AIC component Apparatus for liquid chromatography for separating AIC component

1992-06-09

1994-03-15

Dawson, Robert A.

Liquid purification or separation

With means to add treating material

Chromatography

210 85, 210143, 210656, 422 70, 436 66, 436 67, 436161, 530385, 530413, 530416, 530417, B01D 1508

Patent

active

052943364

ABSTRACT:
Stable hemoglobin A.sub.lc (s-A.sub.lc) can be separated from other hemoglobin components and quantitated in a short time by means of a liquid-chromatographic apparatus comprising a separation column packed with a packing material consisting essentially of a porous substance having a carboxyalkyl group combined thereinto, as ion exchanger, a means for injecting a sample into the separation column, a means for passing one or more eluents through the separation column, and a means for detecting hemoglobin, hemoglobin derivatives or glycosylated hemoglobin, the average particle size of the packing material in dry state being 4 .mu.m or less.

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A. J. Alpert and F. E. Regnier, J. Chromatography, 185 (1979) 375-377, 382-383.
Z. Deyl, K. Macek, and J. Janak, "Liquid Column Chromatography", vol. 3, Elsevier, Amsterdam, 1975, pp. 339, 348-350.
Clinical Chemistry, 27/7, pp. 1261-1263 (1981).
Diabetes, vol. 29, pp. 623-628 (Aug. 1980).

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