Apparatus for ion desolvation in FAIMS

Details Apparatus for ion desolvation in FAIMS Apparatus for ion desolvation in FAIMS

2007-03-13

2007-03-13

Wells, Nikita (Department: 2881)

Radiant energy

Ionic separation or analysis

Cyclically varying ion selecting field means

C250S291000, C250S290000, C250S282000, C250S283000, C250S287000

Reexamination Certificate

active

11133183

ABSTRACT:
Ion separation in a FAIMS analyzer is affected by the presence of neutral species and solvent vapor. A diffuser element, which is fabricated from a porous material, is disposed within a curtain gas chamber adjacent to the FAIMS ion inlet, such that a flow of a curtain gas is blocked from flowing directly out through a curtain gas orifice. The porous material creates a pressure drop across the diffuser and results in the flow of curtain gas being provided out of the curtain gas orifice, along a direction that is approximately perpendicular to a plane containing the curtain gas orifice. The perpendicular gas flow opposes ions traveling toward the curtain gas orifice from an ionization source, thereby desolvating the ions. Providing a perpendicular curtain gas flow for desolvating ions reduces the ion losses that are normally associated with the curtain gas flow deflecting some of the ions away from the curtain gas orifice and toward a curtain plate electrode.

REFERENCES:
patent: 7005633 (2006-02-01), Guevremont et al.

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