Chemical apparatus and process disinfecting – deodorizing – preser – Chemical reactor – For radioactive reactant or product
Patent
1992-06-17
1994-01-04
Warden, Robert J.
Chemical apparatus and process disinfecting, deodorizing, preser
Chemical reactor
For radioactive reactant or product
422903, 436541, 436542, G21C 100
Patent
active
052757897
ABSTRACT:
Materials are labelled with a radioisotope by passing them through a column packed with (a) beads coated with an oxidizing reagent for coupling the radioisotopes to the materials, (b) as anion resin, and (c) a material for trapping elemental isotope, and flowing a mixture of the radioisotope and a solution of the material to be labelled through the column.
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Ferens et al., "High Level Iodination of Monoclonal Antibody Fragments for Radiotherapy" J. Nucl. Med. vol. 25, No. 3 367-370 (1984).
James et al., "A Shielded, Sterile Apparatus for Iodinating Proteins" Med. Lab. Sci. vol. 40, 67-68 (1983).
Henville et al., "A Simple Cheap Remotely Operated System for the Iodination of Proteins" Anal. Biochem vol. 52 336-341 (1973).
Weadock et al., "A Simple Remote System for the High Level Radio-Iodination of Monoclonal Antibodies" J. Nucl. Med. All. Sci. vol. 40 37-41 (1989).
E. I. Du Pont de Nemours and Company
Tran Hien
Warden Robert J.
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