Apparatus for identifying biologically active substances by thei

Details Apparatus for identifying biologically active substances by thei Apparatus for identifying biologically active substances by thei

1995-07-06

1998-02-24

Beisner, William H.

Chemistry: molecular biology and microbiology

Apparatus

Including condition or time responsive control means

4352883, 4352887, 4352991, 4353051, C12M 134

Patent

active

057211353

ABSTRACT:
The present invention relates to a rapid automated device for identifying biologically active substances by their effect on living cells which includes a flow chamber defined by a bottom wall with a plane optical surface through which the content of the chamber can be monitored and a ring shaped wall having an edge adjacent the plane optical surface leaving a gap between the edge and optical surface wherein the width of the gap allows liquid but not matrix to pass. The flow chamber also including an inlet through which fluids can be transported into the chamber and a device to control the distance between the edge and the optical surface wherein the matrix is momentarily allowed to pass.

REFERENCES:
patent: 4734372 (1988-03-01), Rotman
patent: 5312731 (1994-05-01), Engstrom
patent: 5468605 (1995-11-01), Harris et al.

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