Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Patent
1993-04-09
1995-04-11
Beisner, William H.
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
935 85, 604 68, C12M 100
Patent
active
054057795
ABSTRACT:
An apparatus for the particle mediated genetic transformation of organisms in vivo has two parts, a support unit and a hand unit. The hand unit is of a convenient hand manipulable size so that it can be placed readily against the organism the cells of which are to be transformed. The hand unit is connected to the support unit by a flexible umbilical so that the hand unit can be placed where desired. The apparatus is particularly well adapted for the convenient transformation of somatic cells of whole animals or humans.
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Johnston, S. A., "Biolistic Transformation, Microbes to Mice", Nature, 346:776-777 (1990).
Sanford, John C., "The Biolistic Process", Tibtech, vol. 6 (1988).
Sanford, et al., "Delivery of Substances into Cells and Tissues Using a Particle Bombardment Process", Particulate Science and Technology, 5:27-37 (1987).
Burkholder Joseph K.
McCabe Dennis E.
Agracetus, Inc.
Beisner William H.
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