Apparatus for detecting cataractogenesis

Surgery – Truss – Pad

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A61B 300

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active

055402267

ABSTRACT:
An apparatus is disclosed for using quasielastic light scattering to determine the degree of cataractogenesis of a lens in vivo. By collecting and analyzing light scattered from the lens, it is possible, using the temporal autocorrelation function, to produce a signature of cataractogenesis, accounting for scattering due to immobile scatterers. The components of the cataractogenesis can also be detected by comparing the values of the components of the signature of cataractogenesis to frequency distribution of the components taken from populations or by detecting changes in the values of the components of the signature of cataractogenesis as a function of time.

REFERENCES:
patent: 4080264 (1978-03-01), Cohen et al.
patent: 4350163 (1982-09-01), Ford, Jr. et al.
patent: 4702576 (1987-10-01), Magnante
patent: 4711542 (1987-12-01), Ichihashi et al.
patent: 4719912 (1988-01-01), Weinberg
patent: 4957113 (1990-09-01), Benedek
patent: 4993827 (1991-02-01), Benedek et al.
patent: 5072731 (1991-12-01), Taratuta et al.
S. Dubin et al., "Observation of the Spectrum of Light Scattered by Solutions of Biological Macromolecules," Proceedings of the National Academy of Sciences, 57(5): 1164-1171 (1967).
George B. Benedek, "Optical Mixing Spectroscopy, with Applications to Problems in Physics, Chemistry, Biology and Engineering," Polarization Matter and Radiation, Presses Universitaires, Paris, pp. 49-84, (1969).
N. Clark et al., "A Study of Brownian Motion Using Light Scattering," American Journal of Physics, 38(5):575-585, (1970).
T. Tanaka and G. Benedek, "Observation of protein diffusivity in intact human and bovine lenses with application to cataract," Investigative Ophthalmology, 14(6):449-456 (1975).
J. Jedziniak et al., "The Concentration and Localization of Heavy Molecular Weight Aggregates in Aging Normal and Cataractous Human Lenses," Exp. Eye Res., 20:367-369, (1975).
T. Tanaka and C. Ishimoto, "In vivo observation of protein diffusivity in rabbit lenses," Invest. Ophthalmol. Visual Sci. 16(2):135-140 (1977).
J. Jedziniak et al., "Quantitative verification of the existence of high molecular weight protein aggregates in the intact normal human lens by light-scattering spectroscopy," Invest. Ophthalmol. Visual Sci., 17(1):51-57 (1978).
J. Clark and G. Benedek, "Phase Diagram for Cell Cytoplasm from the Calf Lens," Biochemical and Biophysical Research Communications, 95(1):482-489 (1980).
M. Dalaye et al., "Identification of the Scattering Elements Responsible for Lens Opacification in Cold Cataracts," Biophys. J. 37:647-656 (1982).
I. Nishio et al., "In Vivo Observation of Lens Protein Diffusivity in Normal and X-Irradiated Rabbit Lenses," Exp. Eye Res. 39:61-68 (1984).
R. Zeimer and J. Noth, "A New Method of Measuring in vivo the Lens Transmittance, and Study of Lens Scatter, Fluorescence and Transmittance," Ophthalmic Res. 16:246-255 (1984).
R. A. Weale, "Human Lenticular Fluorescence and Transmissivity, and their Effects on Vision," Exp. Eye Research, 41:457-473 (1985).
T. Libondi et al., "In vivo measurement of the aging rabbit lens using quasielastic light scattering," Current Eye Research, 5(6):411-419 (1986).

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