Image analysis – Image enhancement or restoration – Object boundary expansion or contraction
Patent
1994-09-20
1996-10-15
Boudreau, Leo
Image analysis
Image enhancement or restoration
Object boundary expansion or contraction
382128, 382190, G06K 900
Patent
active
055662498
ABSTRACT:
The detection of bubbles in coverslip adhesive. Bubbles in coverslip adhesive may span large areas of the coverslip. An automated cytology system acquires 4 x gray scale images of the slide. Image conditioning is then performed. The conditioned gray scale image is binomially filtered providing a binomial filtered image. The gray scale image is subtracted from the binomial filtered image to produce a high pass enhanced image. An object mask detection is then performed on the high pass enhanced image. Objects are classified to identify bubble edgest. Multiple detections of bubble edges are pieced together to detect bubbles much larger than the area covered by a single image from the detector and the microscope lens. Bubbles are located even if low level image analysis shows gaps in the edges. The cytological system fills in significant gaps in the detected bubble edges. The result is then used for further processing by the automated cytology system.
REFERENCES:
patent: 3824393 (1974-07-01), Brain
patent: 4175860 (1979-11-01), Bacus
patent: 4182046 (1980-01-01), Ludlow et al.
patent: 4191940 (1980-03-01), Polcyn et al.
patent: 4354501 (1982-10-01), Colley et al.
patent: 4354502 (1982-10-01), Colley et al.
patent: 4538299 (1985-08-01), DeForest
patent: 4842900 (1989-06-01), Miyamoto
patent: 4965725 (1990-10-01), Rutenberg
patent: 4980923 (1990-12-01), Kawamoto et al.
patent: 5012524 (1991-04-01), Le Beau
patent: 5072382 (1991-12-01), Kamentsky
patent: 5131049 (1992-07-01), Bloomberg et al.
patent: 5182938 (1993-02-01), Merkel
patent: 5240606 (1993-08-01), Lapidus et al.
patent: 5257182 (1993-10-01), Luck et al.
patent: 5287272 (1994-02-01), Rutenberg et al.
patent: 5315700 (1994-05-01), Johnston et al.
patent: 5361140 (1994-11-01), Hayenga et al.
Bacus, James W. et al., "Optical Microscope System for Standardized Cell Measurements and Analyses", Applied Optics, vol. 26, No. 16, pp. 3280-3293, 15 Aug. 1987.
Bartels, Peter H., et al., "A Self-Learning Computer Program for Cell Recognition", ACTA Cytologica: The Journal of Clinical Cytology, 14:8, pp. 486-494, Oct. 1970.
Breiman, Leo "Chapter 2: Introduction To Tree Classification", pp. 18-58, Classification and Regression Trees, Wadsworth & Brooks/Cole Advanced Books & Software, Pacific Grove, California, 1984.
Duda, Richard O. and Peter E. Hart, "Fisher's Linear Discriminant", Patent Classification and Scene Analysis, Copyright .COPYRGT.1973, pp. 114-119. (No Publisher Or Place Of Publication).
Chapter 39: "The STEPDISC Procedure", SAS/STAT User's Guide, vol. 2, pp. 1493-1509, SAS Institute Inc. (No Date & No Place) (No Author).
Tanaka, Noboru, et al., "Automated Cytologic Screening System (CYBEST Model 4): an Integrated Image Cytometry System", Applied Optics, vol. 26, No. 16, pp. 3301-3307, Aug. 15, 1987. Copyright .COPYRGT.1987 by the Optical Society of America.
Weber, J. E. et al., "Fuzzy Reasoning, Possibility Theory and Probability Theory in Expert Systems for Histopathology", IEEE/Ninth Annual Conference of the Engineering in Medicine and Biology Society, pp. 1560-1562, .COPYRGT.1987 (No Place).
Wied, G. L. et al., "Expert Systems as Classifiers in Diagnostic Cytopathology", IEEE/Ninth Annual Conference of the Engineering in Medicine and Biology/Society, pp. 1915-1917, .COPYRGT.1987. (No Place).
Wied, G. L. et al., "Expert System Design Under Uncertainty of Human Diagnosticians", IEEE/Eighth Annual Conference of the Engineering in Medicine and Biology Society, pp. 757-760, .COPYRGT.1986. (No Place).
Wied, G. L. et al., "Ticas-Stratex, an Expert Diagnostic System For Stratified Cervical Epithelium", IEEE/Ninth Annual Conference of the Engineering in Medicine and Biology Society, pp. 1557-1559, .COPYRGT.1987. (No Place).
Serra, J., Image Analysis and Mathematical Morphology, pp. 372-423, Academic press, 1982. (No Place), "Connectivity Criteria".
Smith, Warren J., "Image Evaluation", Modern Optical Engineering: The Design of Optical Systems, McGraw-Hill Book Company, 1966, pp. 308-325. (New York).
Patten, Jr., Stanley, "Diagnostic Cytopathology of the Uterine Cervix", Basel, Switzerland, Publisher: S. Karger, 1969, 2nd Edition 1978, Third volume in Monographs in Clinical Cytology, edited by G. L. Wied, pp. 10-15.
Kurman, Robert J. et al., "Part 1: Specimen Adequacy" and Part 2: Descriptive Diagnoses, The Bethesda System for Reporting Cervical/Vaginal Cytologic Diagnoses, Springer-Verlag. (New York)-(No Page Number) (No Date).
Dytch, Harvey E. et al., "An Interactive Microcomputer-Based System for the Quantitative Analysis of Stratified Tissue Sections", Analytical and Quantitative Cytology and Histology, vol. 9, No. 1, pp. 69-78, Mar. 1987.
Enslein, Kurt and Peter W. Neurath, "Augmented Stepwise Discriminant Analysis Applied to Two Classification Problems in the Biomedical Field", Computers and Biomedical Research, 2, 568-581 (1969).
Kuan Chih-Chau L.
Rosenlof Mikel D.
Boudreau Leo
NeoPath, Inc.
Tadayon Bijan
LandOfFree
Apparatus for detecting bubbles in coverslip adhesive does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Apparatus for detecting bubbles in coverslip adhesive, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus for detecting bubbles in coverslip adhesive will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1253388