Apparatus for controlling and performing a microbiological or en

Details Apparatus for controlling and performing a microbiological or en Apparatus for controlling and performing a microbiological or en

1989-01-13

1991-12-17

Lacey, David L.

Chemistry: molecular biology and microbiology

Apparatus

Bioreactor

435315, 435316, 435813, 435819, 422132, C12M 136

Patent

active

050734962

ABSTRACT:
To improve the yield and/or reduce the energy cost in carrying out a microbiological or enzymatic process in a reactor and to make the reaction conditions essentially independent of the size of the reactor, it is proposed on make use, as a reactor, of an endless circulation tube in which the reaction components are circulated essentially according to a plug flow and in this process are fed through one or more in-line mixers fitted inside the tube. This method and reactor are suitable in particular for the preparation by fermentation of polysaccharides, especially xanthan, in which water, a production medium containing one or more sugars and nutrient salts and an inoculating material of a suitable aerobic bacterium are introduced into the the reactor tube and exposed to fermentation with air being supplied. Preferably the concentration of a reaction component or a value derived therefrom is measured at at least one point and the reaction velocity is regulated on the basis of the the measurement within critical limits.

REFERENCES:
patent: 3257362 (1966-06-01), Norwood
patent: 3672953 (1972-06-01), Coty et al.
patent: 3847748 (1974-11-01), Gibson et al.
patent: 4181576 (1980-01-01), Malick
Hsu et al., "Oxygen Transfer to Mixed Cultures in Tower Systems", Biotechnology and Bioengineering, vol. 17, pp. 499-514 (1975).

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