Coating apparatus – With vacuum or fluid pressure chamber
Patent
1976-03-22
1977-04-12
Kaplan, Morris
Coating apparatus
With vacuum or fluid pressure chamber
34 58, 118 12, 118 11, 118 52, 233 46, 427 2, 427240, B05C 1108
Patent
active
040168280
ABSTRACT:
Sample preparation apparatus for forming a thin layer of diluted blood specimen on a substrate by centrifugal force includes a sample probe having coaxial blood and diluent conduits coupled to respective reversibly-drivable peristaltic pumps having forward operation intakes connected to a diluent supply. A one-way clutch limits the diluent pump to forward operation and the pumps are geared to produce a blood-to-diluent displacement ratio of 2:1. A substrate holder is mounted on a carriage for selective insertion into and removal from a sealed centrifuge chamber in which it is spun at a high angular rate by a drive motor. Means are provided to form a curtain of flowing liquid within the chamber surrounding the spinning substrate to collect spun-off blood particles and aerosol. The liquid forming the curtain is drained by an exhaust pump which operates after spinning has ceased so as to create a partial vacuum for draining off residual aerosol prior to unsealing the centrifuge chamber.
REFERENCES:
patent: 2412099 (1946-12-01), Sender
patent: 2580131 (1951-12-01), Rowell
patent: 2941499 (1960-06-01), Gutzmer
patent: 2952557 (1960-09-01), Charron
patent: 3280792 (1966-10-01), Heyde
patent: 3705048 (1972-12-01), Staunton
patent: 3906890 (1975-09-01), Amos et al.
Maher, Jr. Francis William
Pirc Vladimir Valentine
Giarratana S. A.
Kaplan Morris
Masselle F. L.
O'Meara J. M.
The Perkin-Elmer Corporation
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